We explored how carboxymethyl-glucan, a compound from yeast, impacts heart health in hypertensive rats. Rats were divided into groups, with some receiving carboxymethyl-glucan for four weeks while others received a placebo.
Results showed that carboxymethyl-glucan improved vascular function and decreased platelet aggregation, especially at a high dose. However, it didn’t lower levels of harmful molecules called reactive oxygen species, indicating it may not fully protect against all cardiovascular issues.
Overall, this compound shows promise in helping to manage hypertension and related complications.
Read More
9
Probiotic lowers cholesterol in hamsters
changes lipidemic profile and gut microbiota in a hamster hypercholesterolemic model.
We explored the effects of the CNCM I-745 probiotic on cholesterol levels and gut bacteria in hamsters with high cholesterol. This controlled study revealed that daily doses significantly lowered total plasma cholesterol and altered gut microbiota. Specifically, we noted that the abundance of certain gut microbes was linked to changes in cholesterol levels and liver gene expression. These findings suggest that this probiotic not only benefits cholesterol levels but also supports gut health, offering potential for safe treatments in managing hypercholesterolemia.
Read More
8
S. boulardii reduces lung injury
Probiotic Saccharomyces boulardii Alleviates Lung Injury by Reduction of Oxidative Stress and Cytokine Response Induced by Supraceliac Aortic Ischemia-Reperfusion Injury in Rats.
We explored the effects of the probiotic Saccharomyces boulardii on lung injury caused by aortic ischemia-reperfusion in rats. Twenty-one rats were divided into three groups, one receiving the probiotic and others receiving saline.
After the aorta was clamped, we noticed that those treated with S. boulardii experienced significantly less lung damage and reduced oxidative stress. This suggests the probiotic helps lower inflammation and oxidative stress markers, potentially leading to better outcomes in cardiovascular procedures.
Read More
Most Useful Reviews
7.5
Improves bowel function
6 people found this helpful
Good for kids and adults! I tried it on an adult during a bacterial illness alongside antibiotic treatment, with beneficial results. The capsules are gelatinous, and one part fits into the other and can be opened. For a 1.5-year-old child, 1/3 of the capsule was given with a confirmed bacterial infection. The child experienced relief from constipation, improved bowel function, and tolerated the illness better. A like would be appreciated if helpful!
Read More
7.5
Enhances overall health
1 people found this helpful
Like other probiotics, Saccharomyces boulardii is a versatile treatment that not only aids in maintaining intestinal health but also enhances overall well-being and prevents stomach diseases. The drug is particularly effective for treating acute diarrhoea and is best taken in the evening to promote optimal development of probiotic microorganisms.
Read More
6
Promotes gut health
1. Beneficial for the gastrointestinal tract (preventing and treating diarrhoea, improving irritable bowel syndrome, alleviating drug-induced gastrointestinal damage, enhancing symptoms of inflammatory bowel disease) 2. Aids in the treatment of H. pylori 3. Assists in managing bacterial, parasitic, and fungal infections. 4. Boosts immune response 5. Increases food tolerance in children 6. Helps prevent cardiovascular disease 7. Supports diabetes and obesity management 8. Improves liver health.
We explored the effects of the CNCM I-745 probiotic on cholesterol levels and gut bacteria in hamsters with high cholesterol. This controlled study revealed that daily doses significantly lowered total plasma cholesterol and altered gut microbiota. Specifically, we noted that the abundance of certain gut microbes was linked to changes in cholesterol levels and liver gene expression. These findings suggest that this probiotic not only benefits cholesterol levels but also supports gut health, offering potential for safe treatments in managing hypercholesterolemia.
Read More
8
S. boulardii reduces lung injury
Probiotic Saccharomyces boulardii Alleviates Lung Injury by Reduction of Oxidative Stress and Cytokine Response Induced by Supraceliac Aortic Ischemia-Reperfusion Injury in Rats.
We explored the effects of the probiotic Saccharomyces boulardii on lung injury caused by aortic ischemia-reperfusion in rats. Twenty-one rats were divided into three groups, one receiving the probiotic and others receiving saline.
After the aorta was clamped, we noticed that those treated with S. boulardii experienced significantly less lung damage and reduced oxidative stress. This suggests the probiotic helps lower inflammation and oxidative stress markers, potentially leading to better outcomes in cardiovascular procedures.
Read More
7
Potential of selenium and zinc postbiotics
Gut Microbiota Modulation by Selenium and Zinc Enrichment Postbiotic on Dysbiosis Associated with Hypertension.
We explored the role of selenium and zinc enriched postbiotic yeast in addressing gut dysbiosis linked to cardiovascular disease. This study involved analyzing the effects of these postbiotics on microbial populations in the digestive system using various scientific methods.
We found that treatment with the enriched postbiotics led to a notable increase in beneficial bacteria and acetic acid levels. These results suggest that selenium and zinc postbiotics may hold therapeutic potential as adjuncts in treating cardiovascular diseases by improving gut health.
Read More
7
Probiotic yeast improves heart-healthy fats
Fatty acids profile, atherogenic and thrombogenic health lipid indices of lyophilized buckwheat sprouts modified with the addition of Saccharomyces cerevisiae var. boulardii.
This innovative study evaluated how adding the probiotic yeast Saccharomyces boulardii to buckwheat sprouts affects their fatty acid composition. Through careful analysis, we found that this modification leads to noteworthy changes in fatty acids, including palmitic and oleic acids.
These changes may enhance the nutritional value of buckwheat sprouts, potentially contributing to a reduced risk of cardiovascular disease. Overall, our findings suggest that probiotic-rich buckwheat sprouts could serve as a functional dietary option for heart health.
Read More
7
Reduced remnant lipoprotein observed
Effect of the Probiotic Saccharomyces boulardii on Cholesterol and Lipoprotein Particles in Hypercholesterolemic Adults: A Single-Arm, Open-Label Pilot Study.
We investigated how the probiotic yeast Saccharomyces boulardii affects blood cholesterol levels in adults with high cholesterol. In this single-arm, open-label pilot study, twelve participants took a specified dose of S. boulardii for eight weeks. While we monitored various cholesterol levels and cardiovascular health markers, results showed a noteworthy reduction in remnant lipoprotein, which could play a role in preventing coronary artery disease. However, overall cholesterol levels did not significantly change during the study.
Good for kids and adults! I tried it on an adult during a bacterial illness alongside antibiotic treatment, with beneficial results. The capsules are gelatinous, and one part fits into the other and can be opened. For a 1.5-year-old child, 1/3 of the capsule was given with a confirmed bacterial infection. The child experienced relief from constipation, improved bowel function, and tolerated the illness better. A like would be appreciated if helpful!
Read More
7.5
Enhances overall health
1 people found this helpful
Like other probiotics, Saccharomyces boulardii is a versatile treatment that not only aids in maintaining intestinal health but also enhances overall well-being and prevents stomach diseases. The drug is particularly effective for treating acute diarrhoea and is best taken in the evening to promote optimal development of probiotic microorganisms.
Read More
6
Promotes gut health
1. Beneficial for the gastrointestinal tract (preventing and treating diarrhoea, improving irritable bowel syndrome, alleviating drug-induced gastrointestinal damage, enhancing symptoms of inflammatory bowel disease) 2. Aids in the treatment of H. pylori 3. Assists in managing bacterial, parasitic, and fungal infections. 4. Boosts immune response 5. Increases food tolerance in children 6. Helps prevent cardiovascular disease 7. Supports diabetes and obesity management 8. Improves liver health.
Read More
7.5
Relieves constipation
1 people found this helpful
This product has consistently been effective in alleviating my constipation. After just a few days of taking the capsules, I restored regular bowel movements.
Read More
7.5
Supports cardiovascular health
Medicine acknowledges the beneficial properties of Saccharomyces in diabetes and obesity; these yeasts rapidly alter the intestinal microbiota, leading to reductions in body fat and improvements in liver steatosis. Regular consumption of S. boulardii also diminishes the risk of coronary heart disease.
Read More
Frequently Asked Questions
Cardiovascular disease (CVD) is a broad term that encompasses a range of heart and blood vessel disorders. This can include conditions such as coronary artery disease, which leads to heart attacks; cerebrovascular disease that results in strokes; and peripheral artery disease affecting blood flow to the limbs. The key risk factors for CVD often include high blood pressure, high cholesterol, obesity, smoking, a sedentary lifestyle, and diabetes. By identifying and managing these risk factors, individuals can significantly reduce their likelihood of developing cardiovascular problems.
Prevention and treatment strategies often involve lifestyle modifications such as adopting a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, alongside engaging in regular physical activity. In some cases, medications might be necessary to control blood pressure or cholesterol levels. Regular check-ups with a healthcare provider are essential for monitoring heart health, especially for individuals with a family history of CVD. Understanding the signs and symptoms of cardiovascular issues—like chest pain, shortness of breath, or fatigue—can help in seeking timely medical attention, ultimately leading to better outcomes.
Saccharomyces boulardii is a beneficial yeast strain known for its probiotic properties. Originally isolated from lychee and mangosteen fruit in the 1920s by French microbiologist Henri Boulard, this yeast is widely recognized for its ability to support digestive health. It is commonly used to prevent and treat diarrhea, especially in cases related to antibiotic use or gastrointestinal infections. Saccharomyces boulardii works by helping to maintain the natural balance of good bacteria in the gut, promoting the growth of beneficial microorganisms, and producing substances that inhibit pathogen growth.
In addition to its anti-diarrheal benefits, research suggests that Saccharomyces boulardii may also contribute to other health benefits, including digestive recovery after gastrointestinal illness and potential support for conditions like irritable bowel syndrome (IBS). While it is generally regarded as safe for most individuals, those with compromised immune systems or central venous catheters should consult healthcare professionals prior to use. As always, it's best to choose high-quality supplements that clearly specify the strain and dosage of Saccharomyces boulardii to ensure efficacy.
Based on user reviews, the timeframe for observing results from this supplement targeting cardiovascular health can vary, but many individuals report noticing beneficial effects within a few days of beginning the regimen. One user highlighted that after just a few days of taking the capsules, they experienced restored regularity in bowel movements, which may indicate a broader improvement in overall health that could support cardiovascular function Read Review.
Additionally, some users believe that consistent intake can lead to longer-term health benefits, such as improved management of diabetes and reduced coronary heart disease risk Read Review. This suggests that while initial results may be observed quickly, the full spectrum of cardiovascular support may develop over weeks or months with regular use. Overall, it’s important to remain consistent with supplementation to fully assess its impact on cardiovascular health.
Scientific research supports the potential of various supplements in influencing cardiovascular health. For instance, a study found that selenium and zinc-enriched postbiotic yeast can help improve gut health, which may play a role in treating cardiovascular diseases by promoting beneficial gut bacteria and acetic acid levels [1]. Furthermore, probiotic yeast like Saccharomyces boulardii has shown promise in modifying cholesterol levels, with one investigation reporting a notable reduction in remnant lipoproteins, which are linked to coronary artery disease [5].
Additional findings suggest that carboxymethyl-glucan derived from yeast can enhance vascular function in hypertensive models, although it does not address all cardiovascular issues [6]. Moreover, supplementation with sodium selenite and selenium-enriched yeast has reduced inflammation and improved antioxidant status in individuals with atherosclerosis, although further studies are needed to establish a clear connection to cardiovascular disease risk [7]. Overall, the current body of research indicates that certain supplements could provide supportive benefits for cardiovascular health, warranting further exploration.
Based on user reviews, individuals have reported various improvements in symptoms when using this supplement. Specific anecdotal experiences highlight the beneficial effects on gastrointestinal health, with one user noting that their 1.5-year-old child found relief from constipation and improved bowel function during a bacterial infection after taking the capsules Read Review. Another reviewer emphasized that the product effectively alleviated their own constipation, restoring regular bowel movements within just a few days of use Read Review.
Moreover, the supplement appears to provide broader health benefits, with users observing relief from acute diarrhea and improvements in conditions like irritable bowel syndrome Read Review. Some also mentioned the potential for supporting immune function and even improving conditions associated with diabetes and cardiovascular health, suggesting a multifaceted benefit that could contribute to overall well-being Read Review. However, it is essential to keep in mind that individual results may vary, and consistent use might be necessary to fully experience these benefits.
Based on user reviews, many individuals have reported positive experiences when combining this supplement with other treatments, particularly for cardiovascular health. A user mentioned that the supplement not only aids in gastrointestinal health but also plays a role in preventing cardiovascular disease, indicating its multifaceted benefits that extend beyond digestion Read Review. Another review highlighted that consistent use has been linked to a reduction in the risk of coronary heart disease, suggesting that it could be beneficial when integrated into a broader health regimen aimed at managing cardiovascular issues Read Review.
Moreover, users noted the importance of the supplement in supporting overall well-being, which could imply that it complements other supplements aimed at cardiovascular and metabolic health. Taking it in combination with other probiotics or treatments might enhance its effectiveness, as some users have found that the supplement contributes to improvements in conditions like diabetes and obesity, which are closely related to cardiovascular health Read Review. As always, individual responses may vary, and it is essential to consult with a healthcare provider when considering the addition of any new supplement to a health routine.
7.5
Relieves constipation
1 people found this helpful
This product has consistently been effective in alleviating my constipation. After just a few days of taking the capsules, I restored regular bowel movements.
7.5
Supports cardiovascular health
Medicine acknowledges the beneficial properties of Saccharomyces in diabetes and obesity; these yeasts rapidly alter the intestinal microbiota, leading to reductions in body fat and improvements in liver steatosis. Regular consumption of S. boulardii also diminishes the risk of coronary heart disease.
7.5
Improves bowel function
6 people found this helpful
Good for kids and adults! I tried it on an adult during a bacterial illness alongside antibiotic treatment, with beneficial results. The capsules are gelatinous, and one part fits into the other and can be opened. For a 1.5-year-old child, 1/3 of the capsule was given with a confirmed bacterial infection. The child experienced relief from constipation, improved bowel function, and tolerated the illness better. A like would be appreciated if helpful!
6
Promotes gut health
1. Beneficial for the gastrointestinal tract (preventing and treating diarrhoea, improving irritable bowel syndrome, alleviating drug-induced gastrointestinal damage, enhancing symptoms of inflammatory bowel disease) 2. Aids in the treatment of H. pylori 3. Assists in managing bacterial, parasitic, and fungal infections. 4. Boosts immune response 5. Increases food tolerance in children 6. Helps prevent cardiovascular disease 7. Supports diabetes and obesity management 8. Improves liver health.
7.5
Enhances overall health
1 people found this helpful
Like other probiotics, Saccharomyces boulardii is a versatile treatment that not only aids in maintaining intestinal health but also enhances overall well-being and prevents stomach diseases. The drug is particularly effective for treating acute diarrhoea and is best taken in the evening to promote optimal development of probiotic microorganisms.
7
Potential of selenium and zinc postbiotics
Gut Microbiota Modulation by Selenium and Zinc Enrichment Postbiotic on Dysbiosis Associated with Hypertension.
We explored the role of selenium and zinc enriched postbiotic yeast in addressing gut dysbiosis linked to cardiovascular disease. This study involved analyzing the effects of these postbiotics on microbial populations in the digestive system using various scientific methods.
We found that treatment with the enriched postbiotics led to a notable increase in beneficial bacteria and acetic acid levels. These results suggest that selenium and zinc postbiotics may hold therapeutic potential as adjuncts in treating cardiovascular diseases by improving gut health.
7
Reduced remnant lipoprotein observed
Effect of the Probiotic Saccharomyces boulardii on Cholesterol and Lipoprotein Particles in Hypercholesterolemic Adults: A Single-Arm, Open-Label Pilot Study.
We investigated how the probiotic yeast Saccharomyces boulardii affects blood cholesterol levels in adults with high cholesterol. In this single-arm, open-label pilot study, twelve participants took a specified dose of S. boulardii for eight weeks. While we monitored various cholesterol levels and cardiovascular health markers, results showed a noteworthy reduction in remnant lipoprotein, which could play a role in preventing coronary artery disease. However, overall cholesterol levels did not significantly change during the study.
7
Cardiovascular benefits of yeast compound
Yeast carboxymethyl-glucan improves endothelial function and inhibits platelet aggregation in spontaneously hypertensive rats.
We explored how carboxymethyl-glucan, a compound from yeast, impacts heart health in hypertensive rats. Rats were divided into groups, with some receiving carboxymethyl-glucan for four weeks while others received a placebo.
Results showed that carboxymethyl-glucan improved vascular function and decreased platelet aggregation, especially at a high dose. However, it didn’t lower levels of harmful molecules called reactive oxygen species, indicating it may not fully protect against all cardiovascular issues.
Overall, this compound shows promise in helping to manage hypertension and related complications.
7
Selenium's potential in heart health
Sodium selenite and Se-enriched yeast supplementation in atherosclerotic patients: Effects on the expression of pyroptosis-related genes and oxidative stress status.
We investigated the effects of daily sodium selenite and Se-enriched yeast on heart health in atherosclerosis patients. In this randomized, double-blind, placebo-controlled trial with 60 participants, we found that these supplements significantly reduced inflammation by lowering pro-inflammatory gene expressions.
We also observed enhancements in antioxidant levels, specifically glutathione peroxidases, while the harmful malondialdehyde levels decreased. Though results are promising, further research is necessary to confirm the true impact of selenium on cardiovascular disease risk.
References
Dinu LD, Gatea F, Matei F, Banciu C, Vamanu E. Gut Microbiota Modulation by Selenium and Zinc Enrichment Postbiotic on Dysbiosis Associated with Hypertension. Curr Vasc Pharmacol. 2024;22:365. 10.2174/0115701611290537240509061549
Durmaz S, Kurtoğlu T, Barbarus E, Çetin NK, Yılmaz M, et al. Probiotic Saccharomyces boulardii Alleviates Lung Injury by Reduction of Oxidative Stress and Cytokine Response Induced by Supraceliac Aortic Ischemia-Reperfusion Injury in Rats. Braz J Cardiovasc Surg. 2021;36:515. 10.21470/1678-9741-2020-0153
Molska M, Reguła J, Rudzińska M, Świeca M. Fatty acids profile, atherogenic and thrombogenic health lipid indices of lyophilized buckwheat sprouts modified with the addition of Saccharomyces cerevisiae var. boulardii. Acta Sci Pol Technol Aliment. 2020;19:483. 10.17306/J.AFS.0866
Briand F, Sulpice T, Giammarinaro P, Roux X. changes lipidemic profile and gut microbiota in a hamster hypercholesterolemic model. Benef Microbes. 2019;10:555. 10.3920/BM2018.0134
Ryan JJ, Hanes DA, Schafer MB, Mikolai J, Zwickey H. Effect of the Probiotic Saccharomyces boulardii on Cholesterol and Lipoprotein Particles in Hypercholesterolemic Adults: A Single-Arm, Open-Label Pilot Study. J Altern Complement Med. 2015;21:288. 10.1089/acm.2014.0063
Bezerra LS, Magnani M, Pimentel TC, de Oliveira JCPL, Freire FMS, et al. Yeast carboxymethyl-glucan improves endothelial function and inhibits platelet aggregation in spontaneously hypertensive rats. Food Funct. 2022;13:5406. 10.1039/d1fo03492h
Roshanravan N, Koche Ghazi MK, Ghaffari S, Naemi M, Alamdari NM, et al. Sodium selenite and Se-enriched yeast supplementation in atherosclerotic patients: Effects on the expression of pyroptosis-related genes and oxidative stress status. Nutr Metab Cardiovasc Dis. 2022;32:1528. 10.1016/j.numecd.2022.02.014